NON-GMO
GLUTEN-FREE
CERTIFIED
FODMAP
FRIENDLY
HALAL
SQF
CERTIFIED
NSF cGMP
PUBLIC BENEFIT
COMPANY
PLASTIC
NEUTRAL
THIRD-PARTY
TESTED
ACEND-CI
15 Doses per Box
$49.50
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Evidence-based nutrition
ACEND-CI
Precision-formulated for the dietary management of chronic inflammation and systemic inflammatory balance.
ACEND-CI has been assigned HCPCS code A9153.
What this means for you: A9153 is the billing code insurers use for medical foods like ACEND-CI, so depending on your plan, it may be eligible for coverage or reimbursement. Learn more →
Purchase options
Cancel or pause anytime
Practitioner-formulated
Third-party tested
Key benefits
Clinically validated ingredients for IL-6, TNF-α and NF-κB signaling
Polyphenols and bioactives for whole-body cellular resilience
Practitioner-formulated, evidence-based dosing
Clean, non-GMO and third-party tested
Formulated around multiple interconnected pathways associated with chronic inflammation
How to use
Daily Serving: Formulated for consistent daily use as part of a foundational nutritional protocol.
Consistency & Adherence: For optimal results, maintain consistent daily use for at least 90 days.
Suggested Use: Take one packet twice daily. Mix each packet thoroughly with 6 oz (180 mL) of fluid. Stir well, as natural sedimentation may occur.
Ingredients + nutrition facts
Quercetin Dihydrate (≥98%), (–)-Epicatechin (≥90%), Dihydroquercetin (Taxifolin, ≥98%), Luteolin (≥98%), Dihydromyricetin (DHM, ≥98%), Grape Seed Extract (≥95% OPCs), CurcuRouge® Curcumin (≥95% Curcuminoids), Thymoquinone (Black Seed Extract, ≥5% TQ), Astaxanthin (Natural, ≥98% All-Trans), Betaine Anhydrous (Trimethylglycine), N-Acetyl L-Cysteine (NAC), Organic Acacia Gum Fiber (FibreGum Bio L, ≥90% Soluble Fiber), Bacillus coagulans (LactoSpore® / MTCC 5856), Vitamin C (Ascorbyl Palmitate), Vitamin E (d-Alpha Tocopheryl Succinate), Vitamin D3 (Cholecalciferol), Vitamin K2 (MK-7), Vitamin B1 (Thiamine Mononitrate), Vitamin B2 (Riboflavin), Vitamin B3 (Niacinamide), Vitamin B5 (Calcium Pantothenate), Vitamin B6 (Pyridoxine HCl), Folate (BioFolate® / L-5-MTHF), Vitamin B12 (Methylcobalamin), Magnesium Citrate, Calcium Citrate, Potassium Bicarbonate, Dicalcium Phosphate, Potassium Chloride, Zinc Citrate, Selenium (Selenomethionine), Manganese Gluconate, Chromium Picolinate, Boron (Bororganic Glycine), Iodine (Potassium Iodide).
Shipping + returns
Shipping: We offer free shipping on orders over $75 and all subscription orders. Standard shipping is $10 for eligible orders under $75.
Orders are typically processed within 1–2 business days. US deliveries generally arrive within 7–10 business days, while international orders may take 14–21 business days. International shipping rates and applicable duties may vary.
Returns & Refunds: Your satisfaction matters to us. We offer a 30-day money-back guarantee on eligible purchases.
Please note that discounted orders, subscription purchases, and international orders are not eligible for returns or refunds. Return shipping costs are the customer's responsibility.
Subscriptions: Enjoy convenient automatic deliveries and complimentary shipping with every subscription order.
Subscriptions require a minimum of one delivery and can be cancelled at any time after your first order ships, with no cancellation fees.
NON-GMO
GLUTEN-FREE
CERTIFIED
FODMAP
FRIENDLY
HALAL
SQF
CERTIFIED
NSF cGMP
PUBLIC BENEFIT
COMPANY
PLASTIC
NEUTRAL
THIRD-PARTY
TESTED
NON-GMO
GLUTEN-FREE
CERTIFIED
FODMAP
FRIENDLY
HALAL
SQF
CERTIFIED
NSF cGMP
PUBLIC BENEFIT
COMPANY
PLASTIC
NEUTRAL
THIRD-PARTY
TESTED
The formula
What’s inside this system.
35 evidence-based ingredients.
Clinically informed ingredients with complementary mechanisms, selected for defined inflammatory roles and synergistic benefits.
Why ACEND-CI
A daily nutrition protocol designed around chronic inflammation.
Chronic inflammation is rarely confined to one tissue or symptom. It reflects a whole-body imbalance in immune signaling, metabolic regulation, vascular integrity, gut-barrier function and cellular repair.
ACEND-CI was designed as the foundational ACEND formula, built to support inflammatory balance across interconnected pathways using clinically informed nutrition.
01
Comprehensive formula
35 evidence-based ingredients with complementary mechanisms.
02
Targeted polyphenols
Bioactive polyphenols at the core of the formula, chosen to support healthy inflammatory signaling and gut-microbiome balance.
03
Gut–immune integration
Prebiotic, probiotic and barrier support at a major inflammatory interface.
04
Dose discipline
Built for long-term use, not ‘mega-dosed’ supplement blends.
05
Quality verification
Third-party testing for raw materials and finished goods.
06
Multi-pathway design
Supports key inflammatory signals and upstream regulators (oxidative stress balance, immune tone).
07
HCPCS code assigned
Assigned HCPCS code A9153.
08
Radical Integrity®
Sourced, tested, certified and designed with a commitment to the most efficacious, safe and sustainable products.
The gut–immune link
Polyphenols are microbiome-supporting nutrients.
Most people think of polyphenols as antioxidants and are unaware of their true pleiotropic nature. Polyphenols also act as selective fuel for beneficial gut microbes. A portion reach the colon, where microbes metabolize them into bioactive compounds, supporting microbial balance, gut barrier integrity and more stable immune signaling.
ACEND-CI is designed with polyphenol diversity plus prebiotic fiber and probiotics to support the gut–immune interface.
Your first 12 weeks
ACEND-CI combines evidence-based polyphenols, targeted bioactives and micelle delivery technology in one daily serving. Here’s how to build the routine.
Subscribe + save 15–20%
Why most customers
subscribe.
Consistency is essential for long-term inflammatory balance and systemic improvements.
SUBSCRIBE + SAVE 15–20%
Cancel or pause anytime
How do I take ACEND-CI?
Take one packet twice daily, mixing each with 6 oz (180 mL) of fluid. Stir well, as natural sedimentation may occur.
ACEND-CI has been assigned HCPCS code A9153, supporting its identification within the healthcare reimbursement system. Insurance coverage and reimbursement eligibility vary by plan and provider.
What does HCPCS code A9153 mean for me?
A HCPCS designation supports medical‑channel classification and signals a higher bar for documentation and standards alignment than typical retail supplements.
DHHS-recognized medical food with an awarded HCPCS code, reflecting its clinical classification and supervised nutritional use. Consult a healthcare professional if pregnant, nursing, managing a medical condition, or taking prescription medications.
Can I take ACEND-CI alongside other supplements or medications?
To be used under medical supervision. If pregnant, consult your healthcare provider before using this product.
How does the subscription work?
Enjoy complete flexibility with the option to skip, reschedule, modify, or cancel your deliveries at any time to suit your needs. Save 15-20% on your first subscription order.
Is ACEND-CI FODMAP Friendly?
ACEND-CI has been independently tested and certified to meet established low-FODMAP standards, providing added confidence for individuals sensitive to fermentable carbohydrates and seeking digestive-friendly nutritional support.
Clinical targets
Clinical targets + biomarkers.
ACEND-CI’s ingredients are clinically validated across biomarkers and pathways associated with chronic inflammation.
[More markers from Science Hub]